2855124-74-0
Chemical Structure
Man-GIcNAc-oxazoline
- CAS No.: 2855124-74-0
- Formula:C20H34N4O12
- Molecular Weight:522.50
InChIKey: PCUZFLPBRXFNRD-MFETVWDSSA-N
SMILES: OC[C@@H](O[C@@]1([H])[C@@](N=C(O1)C)([H])[C@H]2O)[C@H]2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@@H]3O)O)O)COCCOCCOCCN=[N+]=[N-]
Biological Activity: Man-GIcNAc-oxazoline is a disaccharide oxazoline based on Manβ1,4GlcNAc. Man-GIcNAc-oxazoline serves as a donor substrate for transglycosylation in endoglycosidase-mediated antibody Fc glycan remodeling. Man-GIcNAc-oxazoline can be modified with azides, PEG-linked azides, fluorescent probes, biotin groups, ligands or prodrugs. Man-GIcNAc-oxazoline can be used for the synthesis of antibody-drug conjugates (ADC). Man-GIcNAc-oxazoline is applicable for cancer research[1].
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Man-GIcNAc-oxazoline | Man-GIcNAc-oxazoline is a disaccharide oxazoline based on Manβ1,4GlcNAc. Man-GIcNAc-oxazoline serves as a donor substrate for transglycosylation in endoglycosidase-mediated antibody Fc glycan remodeling. Man-GIcNAc-oxazoline can be modified with azides, PEG-linked azides, fluorescent probes, biotin groups, ligands or prodrugs. Man-GIcNAc-oxazoline can be used for the synthesis of antibody-drug conjugates (ADC). Man-GIcNAc-oxazoline is applicable for cancer research. | |||||||||||||||||||||
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