2857007-03-3
2857007-03-3
Chemical Structure
PDE3/4-IN-2
- CAS No.: 2857007-03-3
- Formula:C28H33N5O4
- Molecular Weight:503.59
InChIKey: VJRNDMDKZJPKER-UHFFFAOYSA-N
SMILES: O=C1N=C(N(CCN2C(NCC2)=O)C3=C(C)C=C(C)C=C3C)C=C4C5=C(CCN14)C=C(OC)C(OC)=C5
Biological Activity: PDE3/4-IN-2 is a dual PDE3A and PDE4B1 inhibitor, with an IC50 of 0.13 nM against PDE3A and 50 nM against PDE4B1. PDE3/4-IN-2 exhibits higher systemic exposure and longer retention time in lung tissues in ICR mice. PDE3/4-IN-2 can be used in research on respiratory diseases such as asthma and chronic obstructive pulmonary disease, as well as autoimmune inflammation-related studies[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PDE3/4-IN-2 | 99.33% | PDE3/4-IN-2 is a dual PDE3A and PDE4B1 inhibitor, with an IC50 of 0.13 nM against PDE3A and 50 nM against PDE4B1. PDE3/4-IN-2 exhibits higher systemic exposure and longer retention time in lung tissues in ICR mice. PDE3/4-IN-2 can be used in research on respiratory diseases such as asthma and chronic obstructive pulmonary disease, as well as autoimmune inflammation-related studies. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
