2862774-02-3
2862774-02-3
Chemical Structure
Pomalidomide-C12-NH2 hydrochloride
- CAS No.: 2862774-02-3
- Formula:C25H37ClN4O4
- Molecular Weight:493.04
IUPAC Name: 4-((12-aminododecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
InChIKey: UURKWIVEDYHEIE-UHFFFAOYSA-N
SMILES: NCCCCCCCCCCCCNC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1.Cl
Biological Activity: Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 (HY-139186). PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pomalidomide-C12-NH2 hydrochloride | 96.51% | Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 (HY-139186). PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader. | ||||||||||||||||||||
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Pomalidomide-C7-NH2 hydrochloride | 98.97% | Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC. | ||||||||||||||||||||
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Thalidomide-NH-C8-NH2 | Thalidomide-NH-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | |||||||||||||||||||||
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Thalidomide-NH-C8-NH2 hydrochloride | Thalidomide-NH-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | |||||||||||||||||||||
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Pomalidomide-C11-NH2 | Pomalidomide-C11-NH2 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-C11-NH2 can be connected to the ligand for protein by a linker to form PROTAC. | |||||||||||||||||||||
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Pomalidomide-C11-NH2 hydrochloride | 96.84% | Pomalidomide-C11-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-C11-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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Pomalidomide-C7-NH2 | Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) (Compound 24g) is an E3 Ligase Ligand-Linker Conjugates consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-C7-NH2 can be used for synthesis of PROTACs. | |||||||||||||||||||||
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Thalidomide-NH-C9-NH2 hydrochloride | 99.88% | Thalidomide-NH-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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Thalidomide-NH-C10-NH2 hydrochloride | 95.58% | Thalidomide-NH-C10-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C10-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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Pomalidomide-C12-NH2 | Pomalidomide-C12-NH2 is a conjugate of an E3 ligase and a linker, which can be used for the synthesis of PROTACs, such as PROTAC KRAS G12C degrader-1 (HY-139186). | |||||||||||||||||||||
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Pomalidomide-NH-C13-OH | Pomalidomide-NH-C13-OH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC PI3Kα degrader-1 (HY-174461). | |||||||||||||||||||||
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