2866423-06-3
2866423-06-3
Chemical Structure
OPN-9643
- CAS No.: 2866423-06-3
- Formula:C19H16F3NO2
- Molecular Weight:347.33
InChIKey: XREZTVRYRHMEPO-UHFFFAOYSA-N
SMILES: C=CC(N1CC2=C(C=CC(OC3=CC=C(C(F)(F)F)C=C3)=C2)CC1)=O
Biological Activity: OPN-9643 is a covalent inhibitor targeting the central palmitate binding pocket of TEADs with an IC50 of 15 nM, preventing autopalmitoylation and reducing TEAD-driven luciferase activity and canonical TEAD targets, CTGF and CYR61. OPN-9643 can be used for the research of cancer, such as melanoma[1].
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OPN-9643 | OPN-9643 is a covalent inhibitor targeting the central palmitate binding pocket of TEADs with an IC50 of 15 nM, preventing autopalmitoylation and reducing TEAD-driven luciferase activity and canonical TEAD targets, CTGF and CYR61. OPN-9643 can be used for the research of cancer, such as melanoma. | |||||||||||||||||||||
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