2873460-17-2
Chemical Structure
ZD06519
Synonym(s): 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)
- CAS No.: 2873460-17-2
- Formula:C25H24FN3O7
- Molecular Weight:497.47
InChIKey: SJLICXIYNPAXHJ-VWLOTQADSA-N
SMILES: O=C1N2C(C(C(C2)=C(C3=C4)CNC(OCCO)=O)=NC3=CC(F)=C4C)=CC5=C1COC([C@]5(O)CC)=O
Biological Activity: ZD06519 (7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)) is a camptothecin (HY-16560) analogue and a topoisomerase I inhibitor. ZD06519 is an ADC cytotoxin with a strong bystander effect, inhibiting a variety of malignancies such as HER2-positive and FRα-overexpressing tumors. ZD06519 inhibits DNA cleavage, relaxation, and reconnection processes, inducing tumor cell death. ZD06519 can be used for ADC synthesis and cancer research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZD06519 | 98.88% | ZD06519 (7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)) is a camptothecin (HY-16560) analogue and a topoisomerase I inhibitor. ZD06519 is an ADC cytotoxin with a strong bystander effect, inhibiting a variety of malignancies such as HER2-positive and FRα-overexpressing tumors. ZD06519 inhibits DNA cleavage, relaxation, and reconnection processes, inducing tumor cell death. ZD06519 can be used for ADC synthesis and cancer research. | ||||||||||||||||||||
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