2874263-74-6
2874263-74-6
Chemical Structure
Antituberculosis agent-8
- CAS No.: 2874263-74-6
- Formula:C25H19F3N2O3
- Molecular Weight:452.43
IUPAC Name: 8-fluoro-3-(3-fluoro-2-(3-((6-fluoropyridin-3-yl)methoxy)oxetan-3-yl)phenoxy)-2-methylquinoline
InChIKey: RJZWMLJLHAAMJF-UHFFFAOYSA-N
SMILES: CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC=C(F)N=C5)F
Biological Activity: Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1].
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Antituberculosis agent-8 | Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM. | |||||||||||||||||||||
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