2878598-92-4
2878598-92-4
Chemical Structure
Cav 3.2 inhibitor 2
- CAS No.: 2878598-92-4
- Formula:C32H37F2N3O
- Molecular Weight:517.65
IUPAC Name: 1-(4-(3-fluorophenyl)butyl)-3-(1-(4-(3-fluorophenyl)butyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChIKey: HKFWSOWZPUPCOX-UHFFFAOYSA-N
SMILES: O=C1N(CCCCC2=CC=CC(F)=C2)C3=CC=CC=C3N1C4CCN(CCCCC5=CC=CC(F)=C5)CC4
Biological Activity: Cav 3.2 inhibitor 2 is a Cav3.2 T-type Ca2+ channels inhibitor with an IC50 of 0.09339 μM under -80mV holding potential. Cav 3.2 inhibitor 2 potently suppresses T-channel-dependent somatic and visceral pain in mice. Cav 3.2 inhibitor 2 can be used for the research of intractable pain[1].
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Cav 3.2 inhibitor 2 | Cav 3.2 inhibitor 2 is a Cav3.2 T-type Ca2+ channels inhibitor with an IC50 of 0.09339 μM under -80mV holding potential. Cav 3.2 inhibitor 2 potently suppresses T-channel-dependent somatic and visceral pain in mice. Cav 3.2 inhibitor 2 can be used for the research of intractable pain. | |||||||||||||||||||||
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