2883506-31-6
Chemical Structure
Nrf2/HO-1 activator 2
- CAS No.: 2883506-31-6
- Formula:C20H16F2O5
- Molecular Weight:374.33
IUPAC Name: 9-(2,4-difluorophenyl)-3,5-dihydroxy-2,2-dimethyl-3,4-dihydro-2H,10H-pyrano[2,3-f]chromen-10-one
InChIKey: SXGBVSBQIQXJMR-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C(F)C=C2F)=COC3=C1C4=C(CC(O)C(C)(C)O4)C(O)=C3
Biological Activity: Nrf2/HO-1 activator 2 (compound 13m), difluoro-substituted derivative, is a potent Nrf2/HO-1 activator. Nrf2/HO-1 activator 2 has neuroprotective and antioxidant effects through the Nrf2/HO-1 pathway mediated by phosphorylation of ERK1/2, JNK, or Akt in PC12 cells. Nrf2/HO-1 activator 2 can be used in the research of Parkinson's disease (PD)[1].
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Nrf2/HO-1 activator 2 | Nrf2/HO-1 activator 2 (compound 13m), difluoro-substituted derivative, is a potent Nrf2/HO-1 activator. Nrf2/HO-1 activator 2 has neuroprotective and antioxidant effects through the Nrf2/HO-1 pathway mediated by phosphorylation of ERK1/2, JNK, or Akt in PC12 cells. Nrf2/HO-1 activator 2 can be used in the research of Parkinson's disease (PD). | |||||||||||||||||||||
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