2883580-95-6
2883580-95-6
Chemical Structure
J-1149
- CAS No.: 2883580-95-6
- Formula:C25H24N8O
- Molecular Weight:452.51
InChIKey: GIXYMNJSHSCLBB-LJQANCHMSA-N
SMILES: N[C@H](CC1=CC=CC=C1)C(NCC2=NC(C3=CC=CC(C)=N3)=C(C4=CN5C(C=C4)=NC=N5)N2)=O
Biological Activity: J-1149 is a potent ALK5 inhibitor, with an IC50 value of 0.017 μM. J-1149 also shows weak p38α MAP kinase inhibitory activity, with an IC50 value of 0.435 μM. J-1149 can be used for liver fibrosis research[1].
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J-1149 | J-1149 is a potent ALK5 inhibitor, with an IC50 value of 0.017 μM. J-1149 also shows weak p38α MAP kinase inhibitory activity, with an IC50 value of 0.435 μM. J-1149 can be used for liver fibrosis research. | |||||||||||||||||||||
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