2891562-77-7
2891562-77-7
Chemical Structure
WS-898
- CAS No.: 2891562-77-7
- Formula:C33H25N7OS
- Molecular Weight:567.66
IUPAC Name: (E)-1-(4-((2-(((1H-benzo[d]imidazol-2-yl)methyl)thio)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)phenyl)-3-(naphthalen-2-yl)prop-2-en-1-one
InChIKey: WGQWRCAZEPAXRA-GZTJUZNOSA-N
SMILES: O=C(/C=C/C1=CC=C(C=CC=C2)C2=C1)C3=CC=C(NC4=CC(C)=NC5=NC(SCC6=NC7=C(C=CC=C7)N6)=NN54)C=C3
Biological Activity: WS-898 is a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC50 = 5.0, 3.67, and 3.68 nM, respectively).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WS-898 | 98.51% | WS-898 is a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC50 = 5.0, 3.67, and 3.68 nM, respectively). | ||||||||||||||||||||
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