2896204-90-1
2896204-90-1
Chemical Structure
Anti-inflammatory agent 41
- CAS No.: 2896204-90-1
- Formula:C33H25N3O5
- Molecular Weight:543.57
IUPAC Name: N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxamide
InChIKey: ZTRUKZIXIXWNJP-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C(OC3=CC=C(C=C3)NC(C4=CN(C5=CC=CC=C5C4=O)C6=CC=CC=C6)=O)=CC=N2)C=C1OC
Biological Activity: Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].
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Anti-inflammatory agent 41 | Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway. | |||||||||||||||||||||
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