2901788-27-8
Chemical Structure
Fmoc-Val-Lys-PAB-Exatecan
- CAS No.: 2901788-27-8
- Formula:C58H60FN7O10
- Molecular Weight:1034.14
InChIKey: AUOUFUWRFGMLIN-JFALSYAGSA-N
SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(NC(C=C4)=CC=C4COC(N[C@@H]5C6=C7C(C(N8C7)=CC([C@](O)(C(OC9)=O)CC)=C9C8=O)=NC%10=CC(F)=C(C)C(CC5)=C%106)=O)=O)=O
Biological Activity: Fmoc-Val-Lys-PAB-Exatecan is a derivative of Exatecan (DX-8951) (HY-13631). Fmoc-Val-Lys-PAB-Exatecan can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Fmoc-Val-Lys-PAB-Exatecan is often combined with CD70 mAb to form ADC drugs for the study of tumors with high CD70 expression[1].
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Fmoc-Val-Lys-PAB-Exatecan | Fmoc-Val-Lys-PAB-Exatecan is a derivative of Exatecan (DX-8951) (HY-13631). Fmoc-Val-Lys-PAB-Exatecan can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Fmoc-Val-Lys-PAB-Exatecan is often combined with CD70 mAb to form ADC drugs for the study of tumors with high CD70 expression. | |||||||||||||||||||||
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