2902692-25-3
2902692-25-3
Chemical Structure
TDP-43 degrader-1
- CAS No.: 2902692-25-3
- Formula:C28H29N3O3
- Molecular Weight:455.55
InChIKey: RKKQXGNMFVKLDL-MDZDMXLPSA-N
SMILES: CN1C(C(C(/C=C/C2C3=CC(OC)=C(OCC4=CC=CC=C4)C=C3CCN2)=C1)=C5)=NC=C5OC
Biological Activity: TDP-43 degrader-1 (Compound example 7) is a TDP-43 degrader. TDP-43 degrader-1 reduces the aggregation of TDP-43-positive HuR stress granules in cells and promotes the relocalization of abnormally distributed TDP-43 in the cytoplasm to the nucleus. TDP-43 degrader-1 can be used in the study of amyotrophic lateral sclerosis and Alzheimer's disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TDP-43 degrader-1 | 98.92% | TDP-43 degrader-1 (Compound example 7) is a TDP-43 degrader. TDP-43 degrader-1 reduces the aggregation of TDP-43-positive HuR stress granules in cells and promotes the relocalization of abnormally distributed TDP-43 in the cytoplasm to the nucleus. TDP-43 degrader-1 can be used in the study of amyotrophic lateral sclerosis and Alzheimer's disease. | ||||||||||||||||||||
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