2902715-97-1
2902715-97-1
Chemical Structure
ATR-IN-32
- CAS No.: 2902715-97-1
- Formula:C22H24N6O2
- Molecular Weight:404.46
InChIKey: WJWLAISYUDKJBU-OAHLLOKOSA-N
SMILES: N#CC1(CCOCC1)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5
Biological Activity: ATR-IN-32 is an orally active ATR inhibitor. ATR-IN-32 potently inhibits the proliferation of MIA PaCa-2 cells. ATR-IN-32 exerts significant tumor growth inhibition in mice bearing LOVO and HT-29 xenografts. ATR-IN-32 can be used for the study of cancers mediated by ATR protein kinase, such as colorectal cancer, pancreatic cancer[1].
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ATR-IN-32 | ATR-IN-32 is an orally active ATR inhibitor. ATR-IN-32 potently inhibits the proliferation of MIA PaCa-2 cells. ATR-IN-32 exerts significant tumor growth inhibition in mice bearing LOVO and HT-29 xenografts. ATR-IN-32 can be used for the study of cancers mediated by ATR protein kinase, such as colorectal cancer, pancreatic cancer. | |||||||||||||||||||||
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