2903190-66-7
2903190-66-7
Chemical Structure
TLR9-IN-3
- CAS No.: 2903190-66-7
- Formula:C18H28N8
- Molecular Weight:356.47
InChIKey: ZVQNAXRXGKDLDA-UHFFFAOYSA-N
SMILES: CN1CCN(C2=NC(NCCN(C)C)=NC(NC3=CC=CC=C3)=N2)CC1
Biological Activity: TLR9-IN-3 is a TLR9 antagonist with an IC50 of 0.4 μM. TLR9-IN-3 shows selectivity for TLR4 and TLR8, and inhibits CD69 activation in human whole blood with a corresponding IC50 of 1.1 μM. TLR9-IN-3 can be used in research related to pulmonary fibrosis[1].
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TLR9-IN-3 | TLR9-IN-3 is a TLR9 antagonist with an IC50 of 0.4 μM. TLR9-IN-3 shows selectivity for TLR4 and TLR8, and inhibits CD69 activation in human whole blood with a corresponding IC50 of 1.1 μM. TLR9-IN-3 can be used in research related to pulmonary fibrosis. | |||||||||||||||||||||
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