2907719-42-8
Chemical Structure
MC-GGFG-Eribulin
- CAS No.: 2907719-42-8
- Formula:C65H88N6O18
- Molecular Weight:1241.42
InChIKey: WRAXDQZIOYZOSZ-PLFBBMMKSA-N
SMILES: O=C(CNC(CCCCCN1C(C=CC1=O)=O)=O)NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NC[C@@H](O)C[C@@H](O[C@H]3C[C@H]4O[C@@H](CC[C@@H]5O6)C[C@@H](C)C4=C)[C@H](OC)[C@H]3CC(C[C@@H]7O[C@H]([C@H](O8)[C@H](O[C@H](C9)[C@@H]%10O[C@]98CC[C@H]6CC5=C)[C@H]%10O%11)[C@@H]%11CC7)=O)=O)=O)=O
Biological Activity: MC-GGFG-Eribulin is a linker-payload of a tubulin inhibitor-based cytotoxic agent with an N-substituted maleimide group, conjugated via the MC-GGFG linker. MC-GGFG-Eribulin reacts with the thiol groups of reduced antibodies or antigen-binding fragments to form antibody-drug conjugates. MC-GGFG-Eribulin is applicable for cancer-related research[1].
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MC-GGFG-Eribulin | MC-GGFG-Eribulin is a linker-payload of a tubulin inhibitor-based cytotoxic agent with an N-substituted maleimide group, conjugated via the MC-GGFG linker. MC-GGFG-Eribulin reacts with the thiol groups of reduced antibodies or antigen-binding fragments to form antibody-drug conjugates. MC-GGFG-Eribulin is applicable for cancer-related research. | |||||||||||||||||||||
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