2911655-93-9
2911655-93-9
Chemical Structure
FAK-IN-9
- CAS No.: 2911655-93-9
- Formula:C36H38ClN7O8S
- Molecular Weight:764.25
IUPAC Name: 4-((8-(2-(4-((5-chloro-4-((2-(methylcarbamoyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)acetoxy)octyl)oxy)-3-(phenylsulfonyl)-1,2,5-oxadiazole 2-oxide
InChIKey: IJLTUCWWRYYFBU-UHFFFAOYSA-N
SMILES: CNC(C1=C(C=CC=C1)NC2=C(C=NC(NC3=CC=C(C=C3)CC(OCCCCCCCCOC4=NO[N+]([O-])=C4S(=O)(C5=CC=CC=C5)=O)=O)=N2)Cl)=O
Biological Activity: FAK-IN-9 (Compound 8f) is a potent and orally active FAK inhibitor with an IC50 of 27.44 nM. FAK-IN-9 induces triple-negative breast cancer (TNBC) cell apoptosis[1].
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FAK-IN-9 | FAK-IN-9 (Compound 8f) is a potent and orally active FAK inhibitor with an IC50 of 27.44 nM. FAK-IN-9 induces triple-negative breast cancer (TNBC) cell apoptosis. | |||||||||||||||||||||
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