2914224-54-5
2914224-54-5
Chemical Structure
Antimalarial agent 9
- CAS No.: 2914224-54-5
- Formula:C28H32BrN3O2
- Molecular Weight:522.48
IUPAC Name: 4-((6-bromo-2-methoxyquinolin-3-yl)(1H-imidazol-1-yl)methyl)-2,6-di-tert-butylphenol
InChIKey: MXZOJCYUMGPERG-UHFFFAOYSA-N
SMILES: COC1=NC2=CC=C(C=C2C=C1C(N3C=CN=C3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O)Br
Biological Activity: Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity[1].
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Antimalarial agent 9 | Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity. | |||||||||||||||||||||
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