2918803-89-9
2918803-89-9
Chemical Structure
TRPV4 antagonist 4
- CAS No.: 2918803-89-9
- Formula:C28H32Cl2N6O
- Molecular Weight:539.50
IUPAC Name: N-(5,6-dichloro-1-(1-(4-(1-cyanocyclobutyl)phenyl)piperidin-4-yl)-2-(isopropylamino)-1H-benzo[d]imidazol-4-yl)acetamide
InChIKey: HKOYZUBWZOWYKY-UHFFFAOYSA-N
SMILES: N#CC1(CCC1)C2=CC=C(N3CCC(CC3)N4C(NC(C)C)=NC5=C(NC(C)=O)C(Cl)=C(Cl)C=C54)C=C2
Biological Activity: TRPV4 antagonist 4 is a potent TRPV4 antagonist with an IC50 value of 22.65 nM. TRPV4 antagonist 4 inhibits TRPV4 current. TRPV4 antagonist 4 shows protective effects on acute lung injury[1].
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TRPV4 antagonist 4 | TRPV4 antagonist 4 is a potent TRPV4 antagonist with an IC50 value of 22.65 nM. TRPV4 antagonist 4 inhibits TRPV4 current. TRPV4 antagonist 4 shows protective effects on acute lung injury. | |||||||||||||||||||||
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