2919836-00-1
Chemical Structure
RIP1 kinase inhibitor 4
- CAS No.: 2919836-00-1
- Formula:C23H23N5
- Molecular Weight:369.46
IUPAC Name: 5-((3-(6-phenyl-5,6-dihydrocyclopenta[c]pyrazol-2(4H)-yl)cyclopentyl)ethynyl)pyrimidin-2-amine
InChIKey: MPSUFDFPNVSUSO-UHFFFAOYSA-N
SMILES: NC(N=C1)=NC=C1C#CC2CCC(C2)N3N=C4C(CCC4C5=CC=CC=C5)=C3
Biological Activity: RIP1 kinase inhibitor 4 (Example 3) is a BBB-penetrable RIP1 kinase inhibitor (EC50: <100 nM). RIP1 kinase inhibitor 4 can be used for the research of cell programming necrosis-related diseases[1]. RIP1 kinase inhibitor 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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RIP1 kinase inhibitor 4 | RIP1 kinase inhibitor 4 (Example 3) is a BBB-penetrable RIP1 kinase inhibitor (EC50: <100 nM). RIP1 kinase inhibitor 4 can be used for the research of cell programming necrosis-related diseases. RIP1 kinase inhibitor 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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