2920687-14-3
2920687-14-3
Chemical Structure
NQO2-IN-1
- CAS No.: 2920687-14-3
- Formula:C18H18N2O3
- Molecular Weight:310.35
SMILES: NC1=CC(N=C2)=C(C=C1)C=C2C3=CC(OC)=C(OC)C(OC)=C3
Biological Activity: NQO2-IN-1 (Compound 20b) is the inhibitor for quinone oxidoreductase (NQO) that inhibits NQO2 with an IC50 of 95 nM. NQO2-IN-1 overcomes the resistance of NSCLC cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by induction of ROS and apoptosis[1].
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NQO2-IN-1 | 98.02% | NQO2-IN-1 (Compound 20b) is the inhibitor for quinone oxidoreductase (NQO) that inhibits NQO2 with an IC50 of 95 nM. NQO2-IN-1 overcomes the resistance of NSCLC cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by induction of ROS and apoptosis. | ||||||||||||||||||||
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