2921556-65-0
2921556-65-0
Chemical Structure
ATB1071
- CAS No.: 2921556-65-0
- Formula:C25H27F2NO4
- Molecular Weight:443.48
InChIKey: XMCHHIDSLSIRQP-UHFFFAOYSA-N
SMILES: OCCNCCCOC1=CC(OCC2=CC=C(F)C=C2)=C(OCC3=CC=C(F)C=C3)C=C1
Biological Activity: ATB1071 is a brain-penetrant and orally active p62/SQSTM1 activator. ATB1071 binds to the p62-ZZ domain, promotes PB1-dependent p62 self-polymerization, and activates p62-mediated mitophagy. ATB1071 can be used for the research of Leigh syndrome, cerebral ischemia-reperfusion injury[1].
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ATB1071 | ATB1071 is a brain-penetrant and orally active p62/SQSTM1 activator. ATB1071 binds to the p62-ZZ domain, promotes PB1-dependent p62 self-polymerization, and activates p62-mediated mitophagy. ATB1071 can be used for the research of Leigh syndrome, cerebral ischemia-reperfusion injury. | |||||||||||||||||||||
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