2921605-02-7
2921605-02-7
Chemical Structure
ALK5-IN-87
- CAS No.: 2921605-02-7
- Formula:C25H29ClFN7O2S
- Molecular Weight:546.06
InChIKey: QBINWIRGDHHIBY-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=CC(NC2=CC(C3=CC(Cl)=CC=C3F)=NN=C2SCCO)=C1)CCN4CCN(C)CC4
Biological Activity: ALK5-IN-87 is a potent lung-restricted ALK5 inhibitor with a pKi of 10.13. ALK5-IN-87 exerts antifibrotic activity in a mouse model of lung fibrosis. ALK5-IN-87 can be used for the research of idiopathic pulmonary fibrosis[1].
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ALK5-IN-87 | ALK5-IN-87 is a potent lung-restricted ALK5 inhibitor with a pKi of 10.13. ALK5-IN-87 exerts antifibrotic activity in a mouse model of lung fibrosis. ALK5-IN-87 can be used for the research of idiopathic pulmonary fibrosis. | |||||||||||||||||||||
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