2922-42-1
2922-42-1
Chemical Structure
(-)-3-Dehydroshikimic acid
Synonym(s): 3-DHS; 5-Dehydroshikimic acid
- CAS No.: 2922-42-1
- Formula:C7H8O5
- Molecular Weight:172.14
IUPAC Name: (4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid
InChIKey: SLWWJZMPHJJOPH-PHDIDXHHSA-N
SMILES: OC(C(C[C@H]([C@@H]1O)O)=CC1=O)=O
Biological Activity: (-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(-)-3-Dehydroshikimic acid | 98.35% | (-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions. | ||||||||||||||||||||
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(-)-3-Dehydroshikimic acid (Standard) | ≥98% | (-)-3-Dehydroshikimic acid (Standard) (3-DHS (Standard)) is the analytical standard of (-)-3-Dehydroshikimic acid (HY-N9934). This product is intended for research and analytical applications. (-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions. | ||||||||||||||||||||
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AB 5046B | AB 5046B is a chlorosis-inducing substance can be isolated from Nodulisporium sp. | |||||||||||||||||||||
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AB5046A | AB5046A is a novel chlorosis-inducing substance. AB5046A can be isolated from Nodulisporium sp.. AB5046A induces chlorosis against Japanese barnyard millet. | |||||||||||||||||||||
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Terrein | 99.44% | Terrein is a melanogenesis inhibitor. Terrein induces apoptosis in breast cancer cell lines . Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa. | ||||||||||||||||||||
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HOCPCA | HOCPCA is a compound with neuroprotective activity that improves sensorimotor function in mice after experimental stroke. HOCPCA selectively binds to the CaMKIIα hub domain, modulates signaling of different CaMKII pools, and alleviates abnormal CaMKII signaling after cerebral ischemia. HOCPCA promotes hippocampal neuronal activity and enhances working memory. HOCPCA also normalizes Thr286 autophosphorylation in the cytoplasm after ischemia and downregulates ischemia-specific expression of active CaMKII enzymatic cleavage fragments. HOCPCA binds to the GHB binding site with 27-fold higher affinity than GHB and has good blood-brain barrier penetration ability. | |||||||||||||||||||||
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cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol | cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol (compound VII) is a metabolite of the dioxygenolytic pathway for initial catabolism of Hydrocinnamic acid (3-phenylpropionic acid) (HY-Y1088). | |||||||||||||||||||||
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Shikimic acid | 99.74% | Shikimic acid is a key metabolic intermediate of the aromatic amino acid biosynthesis pathway, found in microbes and plants. | ||||||||||||||||||||
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trans-4-Hydroxy-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-one | trans-4-Hydroxy-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-one (Compound 5) is a monoterpenoid compound found in the fruits of Amomum kravanh. | |||||||||||||||||||||
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Rehmapicrogenin | Rehmapicrogenin, isolated from the root of Rehmannia glutinosa, exhibits potent anti-inflammatory effect by inhibiting iNOS, COX-2 and IL-6. | |||||||||||||||||||||
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4-Hydroxy-2,6,6-trimethyl-1-cyclohexenecarboxylic acid | 4-Hydroxy-2,6,6-trimethyl-1-cyclohexenecarboxylic acid is a Monoterpenoids product that can be isolated from the herbs of Salvia dugesii. | |||||||||||||||||||||
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Mesalazine impurity 11 | Mesalazine impurity 11 is an impurity of Mesalazine. | |||||||||||||||||||||
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References
- [1]. Wang H, et al. Transcriptomic and Metabolic Analysis of Fruit Development and Identification of Genes Involved in Raffinose and Hydrolysable Tannin Biosynthesis in Walnuts. Journal of agricultural and food chemistry. 2021 Jul 21;69(28):8050-8062.
- [2]. Davis BD. Aromatic Biosynthesis: VI. Resistance to Inhibition by an Accumulated Metabolite, 5-Dehydroshikimic Acid, and Its Significance for the Mechanism of Drug Resistance. Proc Natl Acad Sci U S A. 1953 May;39(5):363-6.
- [3]. Chang YC, et al. Antioxidant activity of 3-dehydroshikimic acid in liposomes, emulsions, and bulk oil. Journal of agricultural and food chemistry. 2003 Apr 23;51(9):2753-7. [Content Brief]
