2923208-52-8
2923208-52-8
Chemical Structure
ZNF207-IN-1
- CAS No.: 2923208-52-8
- Formula:C32H32BrN3O
- Molecular Weight:554.52
InChIKey: RZJZAWPSUBSTEJ-UHFFFAOYSA-N
SMILES: N#CC1(CC2(C3=C(C1C4=C2C=CC=C4)C=CC=C3)Br)C(NCCC5CCN(CC5)CC6=CC=CC=C6)=O
Biological Activity: ZNF207-IN-1 is an orally active and brain-penetrant ZNF207 inhibitor with a target KD of 67 nM. ZNF207-IN-1 binds directly to ZNF207, downregulates stem-related genes and weakens glioma cell stemness. ZNF207-IN-1 hinders tumorigenesis and migration and promotes apoptosis. ZNF207-IN-1 can be used for the research of glioma[1].
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ZNF207-IN-1 | 98.03% | ZNF207-IN-1 is an orally active and brain-penetrant ZNF207 inhibitor with a target KD of 67 nM. ZNF207-IN-1 binds directly to ZNF207, downregulates stem-related genes and weakens glioma cell stemness. ZNF207-IN-1 hinders tumorigenesis and migration and promotes apoptosis. ZNF207-IN-1 can be used for the research of glioma. | ||||||||||||||||||||
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