2923865-76-1
2923865-76-1
Chemical Structure
KRAS G12C-IN-70
- CAS No.: 2923865-76-1
- Formula:C26H19ClF2N6O2S
- Molecular Weight:552.98
InChIKey: OGCZIFCMYITYON-GFCCVEGCSA-N
SMILES: C=CC(N1CCN2C(C3=C(C4=C(C5=C6C(SC(N)=C6C#N)=C(F)C=C5)C(F)=C3)N(N=C4Cl)CC[C@@H]2C1)=O)=O
Biological Activity: KRAS G12C-IN-70 is a selective KRAS G12C mutant inhibitor. KRAS G12C-IN-70 blocks KRAS G12C-mediated downstream signaling pathways (e.g., RAF-MEK-ERK) and inhibits tumor cell proliferation. KRAS G12C-IN-70 is promising for research of KRAS G12C mutation-related tumors (such as non-small cell lung cancer, colorectal cancer)[1].
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KRAS G12C-IN-70 | KRAS G12C-IN-70 is a selective KRAS G12C mutant inhibitor. KRAS G12C-IN-70 blocks KRAS G12C-mediated downstream signaling pathways (e.g., RAF-MEK-ERK) and inhibits tumor cell proliferation. KRAS G12C-IN-70 is promising for research of KRAS G12C mutation-related tumors (such as non-small cell lung cancer, colorectal cancer). | |||||||||||||||||||||
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