2924270-62-0
Chemical Structure
Antifungal agent-170
- CAS No.: 2924270-62-0
- Formula:C22H19F5N6O2
- Molecular Weight:494.42
InChIKey: LDNIBRGTDJRCDE-LHSJRXKWSA-N
SMILES: C[C@@H](C1=NN(CC2=CC=C(OC(F)(F)F)C=C2)C=C1)[C@@](CN3N=NN=C3)(O)C4=C(F)C=C(F)C=C4
Biological Activity: Antifungal agent-170 is an Antifungal agent. Antifungal agent-170 potently inhibits the growth of recombinant Saccharomyces cerevisiae strains expressing wild-type and mutant fungal CYP51 enzymes. Antifungal agent-170 potently inhibits the growth of Candida albicans, Candida glabrata, Candida krusei, Cryptococcus neoformans and Cryptococcus gattii. Antifungal agent-170 provides survival benefits in the Galleria mellonella (greater wax moth) infection model. Antifungal agent-170 can be used for the research of invasive fungal infections[1].
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Antifungal agent-170 | Antifungal agent-170 is an Antifungal agent. Antifungal agent-170 potently inhibits the growth of recombinant Saccharomyces cerevisiae strains expressing wild-type and mutant fungal CYP51 enzymes. Antifungal agent-170 potently inhibits the growth of Candida albicans, Candida glabrata, Candida krusei, Cryptococcus neoformans and Cryptococcus gattii. Antifungal agent-170 provides survival benefits in the Galleria mellonella (greater wax moth) infection model. Antifungal agent-170 can be used for the research of invasive fungal infections. | |||||||||||||||||||||
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