2925085-21-6
2925085-21-6
Chemical Structure
CRBN ligand-454
- CAS No.: 2925085-21-6
- Formula:C13H10N4O3
- Molecular Weight:270.25
IUPAC Name: 8-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)quinazoline-2-carbaldehyde
InChIKey: FFPHRKBOPORZOV-UHFFFAOYSA-N
SMILES: O=CC1=NC=C2C=CC=C(C2=N1)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-454 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-454 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-454 | CRBN ligand-454 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-454 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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