2925926-80-1
2925926-80-1
Chemical Structure
Quorum sensing-IN-2
- CAS No.: 2925926-80-1
- Formula:C19H13F2NO3
- Molecular Weight:341.31
InChIKey: NQPBBFRTQLYIMO-UHFFFAOYSA-N
SMILES: O=C(C(CNC(C1=CC=C(C=C1)F)=O)=C2C3=CC=C(C=C3)F)OC2=C
Biological Activity: Quorum sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1[1].
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Quorum sensing-IN-2 | Quorum sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1. | |||||||||||||||||||||
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