2929345-46-8
2929345-46-8
Chemical Structure
MKLP2-IN-1
- CAS No.: 2929345-46-8
- Formula:C23H19BrFN3O2
- Molecular Weight:468.32
SMILES: FC1=C(C)C=CC(CN2C(CC(C3=NN=C(C4CC4)O3)=C(Br)C5=CC=CC=C52)=O)=C1
Biological Activity: MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 with good oral bioavailability. MKLP2-IN-1 inhibits the microtubule-stimulated ATPase activity of recombinant MKLP2 in vitro and suppresses tumor growth in a mouse Calu-6 lung cancer model[1].
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MKLP2-IN-1 | MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 with good oral bioavailability. MKLP2-IN-1 inhibits the microtubule-stimulated ATPase activity of recombinant MKLP2 in vitro and suppresses tumor growth in a mouse Calu-6 lung cancer model. | |||||||||||||||||||||
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