2933124-32-2
2933124-32-2
Chemical Structure
PROTAC BRM/BRG1 degrader-2
- CAS No.: 2933124-32-2
- Formula:C50H60N12O5S
- Molecular Weight:941.15
InChIKey: XCHURTCALGLHFP-PPZQHQRRSA-N
SMILES: NC(C1=C2C=C(C3=C(O)C=CC=C3)N=N1)=NN2C(CC4)CCN4C5=NC=C([C@H]6CC[C@H](C(N[C@@H](C(C)(C)C)C(N7C[C@H](O)C[C@H]7C(N[C@H](C8=CC=C(C9=C(C)N=CS9)C=C8)C)=O)=O)=O)CC6)C=N5
Biological Activity: PROTAC BRM/BRG1 degrader-2 (Example.004) is a PROTAC BRM/BRG1 degrader (DC50: < 10 nM in A549 cell; IC50: 15 nM for A549)[1].
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PROTAC BRM/BRG1 degrader-2 | PROTAC BRM/BRG1 degrader-2 (Example.004) is a PROTAC BRM/BRG1 degrader (DC50: < 10 nM in A549 cell; IC50: 15 nM for A549). | |||||||||||||||||||||
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