2934318-93-9
2934318-93-9
Chemical Structure
(S)-UFR2709 hydrochloride
- CAS No.: 2934318-93-9
- Formula:C13H18ClNO2
- Molecular Weight:255.74
IUPAC Name: (S)-(1-methylpyrrolidin-2-yl)methyl benzoate hydrochloride
InChIKey: IJJHQEXZNVTJHI-YDALLXLXSA-N
SMILES: O=C(C1=CC=CC=C1)OC[C@H](CCC2)N2C.Cl
Biological Activity: (S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction[1][2].
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(S)-UFR2709 hydrochloride | 98.10% | (S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction. | ||||||||||||||||||||
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References
- [1]. Gabriel Quiroz, et al. UFR2709, a Nicotinic Acetylcholine Receptor Antagonist, Decreases Ethanol Intake in Alcohol-Preferring Rats. Front Pharmacol. 2019 Dec 3;10:1429. [Content Brief]
- [2]. Franco Viscarra, et al. Nicotinic Antagonist UFR2709 Inhibits Nicotine Reward and Decreases Anxiety in Zebrafish. Molecules. 2020 Jun 30;25(13):2998. [Content Brief]
