2936625-34-0
2936625-34-0
Chemical Structure
PF-07328948
- CAS No.: 2936625-34-0
- Formula:C16H8F4O3S
- Molecular Weight:356.29
InChIKey: FXLDAQFHCAENIV-UHFFFAOYSA-N
SMILES: FC1=C(C=C(C(F)=C1OC)C2=C(C(O)=O)SC3=CC(F)=CC=C23)F
Biological Activity: PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-07328948 | 99.88% | PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats. | ||||||||||||||||||||
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