2939850-17-4
2939850-17-4
Chemical Structure
Balomenib
Synonym(s): ZE63-0302
- CAS No.: 2939850-17-4
- Formula:C33H34F3N7O2
- Molecular Weight:617.66
InChIKey: GTFGTNVSMRVPEN-VWLOTQADSA-N
SMILES: FC(F)(F)CC1=CC(C(N(C2)CC2(CC3)CCN3CC4=CC=C(N(C(C#N)=C5)C[C@@H]6CNC(CO6)=O)C5=C4C)=NC=N7)=C7C=C1
Biological Activity: Balomenib (ZE63-0302) is an orally bioavailable menin-KMT2A interaction inhibitor. Balomenib disrupts menin-KMT2A binding, reverses aberrant HOX gene expression. Balomenib inhibits Meis1 mRNA expression in KMT2A-rearranged acute myeloid leukemia cells. Balomenib can be used for the research of leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Balomenib | 99.81% | Balomenib (ZE63-0302) is an orally bioavailable menin-KMT2A interaction inhibitor. Balomenib disrupts menin-KMT2A binding, reverses aberrant HOX gene expression. Balomenib inhibits Meis1 mRNA expression in KMT2A-rearranged acute myeloid leukemia cells. Balomenib can be used for the research of leukemia. | ||||||||||||||||||||
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