29424-96-2
Chemical Structure
4',7-Di-O-methylnaringenin
Synonym(s): (-)-Naringenin 4',7-dimethyl Ether; (-)-NRG-DM
- CAS No.: 29424-96-2
- Formula:C17H16O5
- Molecular Weight:300.31
IUPAC Name: (S)-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)chroman-4-one
InChIKey: CKEXCBVNKRHAMX-HNNXBMFYSA-N
SMILES: O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(OC)=CC(O)=C13
Biological Activity: 4',7-Di-O-methylnaringenin ((−)-NRG-DM) is a flavonoid found in Renealmia alpinia[1]. (−)-NRG-DM inhibits Nav1.7, Nav1.8 and Kv2.1 channels and has analgesic activity. Intraperitoneal administration of (−)-NRG-DM dose-dependently attenuated pain in a formalin-induced mouse inflammatory pain model and mustard oil-induced mouse colorectal pain model[2].
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4',7-Di-O-methylnaringenin | 99.20% | 4',7-Di-O-methylnaringenin ((−)-NRG-DM) is a flavonoid found in Renealmia alpinia. (−)-NRG-DM inhibits Nav1.7, Nav1.8 and Kv2.1 channels and has analgesic activity. Intraperitoneal administration of (−)-NRG-DM dose-dependently attenuated pain in a formalin-induced mouse inflammatory pain model and mustard oil-induced mouse colorectal pain model[2]. | ||||||||||||||||||||
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