2944114-41-2
2944114-41-2
Chemical Structure
Enpp-1-IN-29
- CAS No.: 2944114-41-2
- Formula:C18H14F2N4O5S
- Molecular Weight:436.39
SMILES: O=C1OCC2=CN=C3N=C(C=CC3=C2N1CC4=C(C=C(S(=O)(N)=O)C=C4F)F)OC
Biological Activity: Enpp-1-IN-29 (Compound 1) is a highly selective ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor (IC50=0.05 nM). Enpp-1-IN-29 is promising for research of ENPP1-overexpressing cancers (e.g., breast cancer, head/neck cancer, metastatic chromosome-unstable tumors) and immune-related diseases (e.g., autoimmune disorders, tumor immune evasion)[1].
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Enpp-1-IN-29 | Enpp-1-IN-29 (Compound 1) is a highly selective ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor (IC50=0.05 nM). Enpp-1-IN-29 is promising for research of ENPP1-overexpressing cancers (e.g., breast cancer, head/neck cancer, metastatic chromosome-unstable tumors) and immune-related diseases (e.g., autoimmune disorders, tumor immune evasion). | |||||||||||||||||||||
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