2947497-65-4
2947497-65-4
Chemical Structure
OAT-4828
- CAS No.: 2947497-65-4
- Formula:C28H28F3N5O3S
- Molecular Weight:571.61
InChIKey: UMDAQLNUNDVRJT-YJPTXTSQSA-N
SMILES: CN[C@H]1CCN(C1)C(C2=C(C=C(N=C2C3=C4SC(CN5C(C6C(C6(C)C)C5=O)=O)=CC4=NC=C3)C(F)(F)F)C)=O
Biological Activity: OAT-4828 is an orally active ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 32 nM. OAT-4828 induces antileukemic activity in B-cell-derived non-Hodgkin's lymphoma models via inhibition of USP7. OAT-4828 is applicable to research related to chronic lymphocytic leukemia[1].
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OAT-4828 | OAT-4828 is an orally active ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 32 nM. OAT-4828 induces antileukemic activity in B-cell-derived non-Hodgkin's lymphoma models via inhibition of USP7. OAT-4828 is applicable to research related to chronic lymphocytic leukemia. | |||||||||||||||||||||
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