2953426-96-3
2953426-96-3
Chemical Structure
CRBN ligand-901
- CAS No.: 2953426-96-3
- Formula:C19H18N2O5
- Molecular Weight:354.36
InChIKey: KVHNEFFZZAWTKY-UHFFFAOYSA-N
SMILES: O=C(O)CCCC#CC1=CC=C(CN(C2CCC(NC2=O)=O)C3=O)C3=C1
Biological Activity: CRBN ligand-901 (5d in Scheme 2) is a ligand for Cereblon (CRBN). CRBN ligand-901 can be linked to target protein ligands (e.g., VP1 ligand-1) via a linker to form PROTAC molecules (e.g., Jun15702 (HY-182924))[1].
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CRBN ligand-901 | CRBN ligand-901 (5d in Scheme 2) is a ligand for Cereblon (CRBN). CRBN ligand-901 can be linked to target protein ligands (e.g., VP1 ligand-1) via a linker to form PROTAC molecules (e.g., Jun15702 (HY-182924)). | |||||||||||||||||||||
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