2956791-61-8
2956791-61-8
Chemical Structure
NLRP3-IN-21
- CAS No.: 2956791-61-8
- Formula:C20H13Cl2F3N6O2S
- Molecular Weight:529.32
InChIKey: LBCNPILPPQLOKG-UHFFFAOYSA-N
SMILES: O=C1N(N=C(N2C1=CC3=C2C=C(S3)Cl)C(C)C)CC4=NN=C(O4)C5=CC=C(N=C5Cl)C(F)(F)F
Biological Activity: NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].
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NLRP3-IN-21 | 98.97% | NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly. | ||||||||||||||||||||
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