2963606-11-1
2963606-11-1
Chemical Structure
HBC-12551
- CAS No.: 2963606-11-1
- Formula:C34H41FN8O5
- Molecular Weight:660.74
InChIKey: DJYDBUUONPEWRR-JOCHJYFZSA-N
SMILES: FC(C=C1)=CC(C(NCC(C=C2)=CC=C2N(N=C3)C(C(N)=O)=C3NC(C=C4)=NC([C@@H](C)OC)=C4N(CC5)CCN5CCOC)=O)=C1OC
Biological Activity: HBC-12551 is an orally active BTK inhibitor (IC50 in HEK293 cells: 1.31 nM for BTK; 2.18 nM for BTKC481S). HBC-12551 has antitumor activity against diffuse large B-cell lymphoma[1].
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HBC-12551 | HBC-12551 is an orally active BTK inhibitor (IC50 in HEK293 cells: 1.31 nM for BTK; 2.18 nM for BTKC481S). HBC-12551 has antitumor activity against diffuse large B-cell lymphoma. | |||||||||||||||||||||
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