2966090-78-6

PD-1/PD-L1-IN-26 Chemical Structure
2966090-78-6

Chemical Structure

PD-1/PD-L1-IN-26

  • CAS No.: 2966090-78-6
  • Formula:C43H52N4O8
  • Molecular Weight:752.89

IUPAC Name: 2-(hydroxymethyl)-2-((4-((3'-(3-(4-(hydroxymethyl)piperidin-1-yl)propoxy)-2-methyl-[1,1'-biphenyl]-3-yl)methoxy)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)methoxy)benzyl)amino)propane-1,3-diol

InChIKey: JGZQAQGOLLTOQP-UHFFFAOYSA-N

SMILES: CC1=C(C=CC=C1C2=CC=CC(OCCCN3CCC(CC3)CO)=C2)COC4=CC=C(C(OCC5=NN=C(O5)C6=CC=CC=C6)=C4)CNC(CO)(CO)CO

Biological Activity: PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-144746
PD-1/PD-L1-IN-26 PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References