2969205-90-9
2969205-90-9
Chemical Structure
AAK1-IN-8
- CAS No.: 2969205-90-9
- Formula:C24H23N5O3
- Molecular Weight:429.47
InChIKey: QUXWMXHXYXTBRA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C=C1OCCOCC/N=C3C=CN4N=CC2=C4N\3)NCC5=CC=CC=C5
Biological Activity: AAK1-IN-8 (Compound 18) is a pan-NAK inhibitor. AAK1-IN-8 inhibits AAK1 and GAK (EC50 values are 50 and 190 nM, respectively). AAK1-IN-8 inhibits the phosphorylation of AP2-µ2 subunit at T156[1].
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AAK1-IN-8 | AAK1-IN-8 (Compound 18) is a pan-NAK inhibitor. AAK1-IN-8 inhibits AAK1 and GAK (EC50 values are 50 and 190 nM, respectively). AAK1-IN-8 inhibits the phosphorylation of AP2-µ2 subunit at T156. | |||||||||||||||||||||
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