2978244-71-0
Chemical Structure
GLP-1R modulator-1
- CAS No.: 2978244-71-0
- Formula:C41H38ClFN6O4
- Molecular Weight:733.23
InChIKey: BPRIIQQQFREMQY-GJPBYDNQSA-N
SMILES: C[C@@]1(C2=C(C=C(C=C2)Cl)F)OC3=C(C4=CCN(CC5=NC6=CC(NC(C7=CC(C)=C(NN=C8C)C8=C7)=O)=CC=C6N5C[C@@H]9CCO9)CC4)C=CC=C3O1
Biological Activity: GLP-1R modulator-1 (Compound 384) is an orally active, potent selective glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R modulator-1 activates G-protein coupled signaling, elevates intracellular cAMP levels, promotes insulin secretion, delays gastric emptying and suppresses appetite. GLP-1R modulator-1 is promising for research of type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH)[1].
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GLP-1R modulator-1 | GLP-1R modulator-1 (Compound 384) is an orally active, potent selective glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R modulator-1 activates G-protein coupled signaling, elevates intracellular cAMP levels, promotes insulin secretion, delays gastric emptying and suppresses appetite. GLP-1R modulator-1 is promising for research of type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH). | |||||||||||||||||||||
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