2982502-32-7
2982502-32-7
Chemical Structure
FXR agonist 9
- CAS No.: 2982502-32-7
- Formula:C28H30N2O5
- Molecular Weight:474.55
InChIKey: PXVVIZGYRBAVHT-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC=C1C(NC2=CC=CC(C(O)=O)=C2)=O)CCCOC3=CC=C(C(C)(C)C)C=C3
Biological Activity: FXR agonist 9 (compound 26) is an oral active and selectivity FXR partial agonist with the EC50 of 0.09 µM (75.13 % maximum efficacy). FXR agonist 9 ameliorates pathological features in HFD and CCl4(HY-Y0298)-induced metabolic dysfunction-associated steatohepatitis mice[1].
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FXR agonist 9 | FXR agonist 9 (compound 26) is an oral active and selectivity FXR partial agonist with the EC50 of 0.09 µM (75.13 % maximum efficacy). FXR agonist 9 ameliorates pathological features in HFD and CCl4(HY-Y0298)-induced metabolic dysfunction-associated steatohepatitis mice. | |||||||||||||||||||||
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