2984765-48-0
2984765-48-0
Chemical Structure
(S)-NIK SMI1
- CAS No.: 2984765-48-0
- Formula:C20H19N3O4
- Molecular Weight:365.38
IUPAC Name: (S)-6-(3-((3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide
InChIKey: LQSHXYHWYGKAMX-HXUWFJFHSA-N
SMILES: O=C(N)C1=NC(C2=CC=CC(C#C[C@@]3(O)CCN(C)C3=O)=C2)=CC(OC)=C1
Biological Activity: (S)-NIK SMI1 is the isomer of NIK SMI1 (HY-112433), and can be used as an experimental control. NIK SMI1 is a potent, selective NF-κB inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-NIK SMI1 | 99.29% | (S)-NIK SMI1 is the isomer of NIK SMI1 (HY-112433), and can be used as an experimental control. NIK SMI1 is a potent, selective NF-κB inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM. | ||||||||||||||||||||
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