2986729-29-5
Chemical Structure
Antifungal agent 28
- CAS No.: 2986729-29-5
- Formula:C22H29N5OS
- Molecular Weight:411.56
IUPAC Name: (1S,2R)-N1-(5-(2-(4-(tert-butyl)phenyl)-4-methylthiazol-5-yl)-1,3,4-oxadiazol-2-yl)cyclohexane-1,2-diamine
InChIKey: QQJTWYXHXZQIOH-SJORKVTESA-N
SMILES: CC1=C(C2=NN=C(N[C@H]3[C@H](CCCC3)N)O2)SC(C4=CC=C(C=C4)C(C)(C)C)=N1
Biological Activity: Antifungal agent 28 (compound 18) is a potent and selective antifungal agent. Antifungal agent 28 inhibits pathogenic strains of C. albicans and non-albicans species including fluconazole-resistant strains. Antifungal agent 28 inhibits Cryptococcus and Aspergillus strains. Antifungal agent 28 disrupts mature Candida biofilm[1].
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Antifungal agent 28 | Antifungal agent 28 (compound 18) is a potent and selective antifungal agent. Antifungal agent 28 inhibits pathogenic strains of C. albicans and non-albicans species including fluconazole-resistant strains. Antifungal agent 28 inhibits Cryptococcus and Aspergillus strains. Antifungal agent 28 disrupts mature Candida biofilm. | |||||||||||||||||||||
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