2989453-29-2
2989453-29-2
Chemical Structure
Mps1-IN-3 hydrochloride
- CAS No.: 2989453-29-2
- Formula:C26H32ClN7O4S
- Molecular Weight:574.09
IUPAC Name: 1-(4-((6-((2-(isopropylsulfonyl)phenyl)amino)-9H-purin-2-yl)amino)-3-methoxyphenyl)piperidin-4-ol hydrochloride
InChIKey: BDKTZCBXQCCHRK-UHFFFAOYSA-N
SMILES: OC1CCN(C2=CC=C(NC3=NC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5N=CNC5=N3)C(OC)=C2)CC1.[H]Cl
Biological Activity: Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mps1-IN-3 hydrochloride | 98.04% | Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model. | ||||||||||||||||||||
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