2990549-94-3
2990549-94-3
Chemical Structure
Steroid sulfatase/17β-HSD1-IN-4
- CAS No.: 2990549-94-3
- Formula:C18H17N3O4S2
- Molecular Weight:403.48
IUPAC Name: 4-(4-(methyl(o-tolyl)carbamoyl)thiazol-2-yl)phenyl sulfamate
InChIKey: OFOIBULGTCOPNO-UHFFFAOYSA-N
SMILES: O=S(OC1=CC=C(C2=NC(C(N(C)C3=CC=CC=C3C)=O)=CS2)C=C1)(N)=O
Biological Activity: Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS activity with anIC50 value of 63 nM. Steroid sulfatase/17β-HSD1-IN-4 can be used in the study of endometriosis and other estrogen-dependent diseases[1].
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Steroid sulfatase/17β-HSD1-IN-4 | Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS activity with anIC50 value of 63 nM. Steroid sulfatase/17β-HSD1-IN-4 can be used in the study of endometriosis and other estrogen-dependent diseases. | |||||||||||||||||||||
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