2991023-13-1
2991023-13-1
Chemical Structure
(R)-PVTX-405
- CAS No.: 2991023-13-1
- Formula:C30H31N5O4
- Molecular Weight:525.60
InChIKey: SITNTOVOBBQZJQ-RUZDIDTESA-N
SMILES: O=C1N(CC2=C1C=CC3=C2OCC34CCN(CC5=CC=CC(C(C=N6)=CN6C)=C5)CC4)[C@@H](C7=O)CCC(N7)=O
Biological Activity: (R)-PVTX-405 is a IKZF2 molecular glue degrader with a DC50 of 4.1 nM. (R)-PVTX-405 is the (R)-enantiomer of PVTX-405 (HY-172930). PVTX-405 is an orally active IKZF2 molecular glue degrader that significantly inhibits MC38 tumor growth in mouse tumor xenograft models. (R)-PVTX-405 can be used in cancer-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(R)-PVTX-405 | 96.01% | (R)-PVTX-405 is a IKZF2 molecular glue degrader with a DC50 of 4.1 nM. (R)-PVTX-405 is the (R)-enantiomer of PVTX-405 (HY-172930). PVTX-405 is an orally active IKZF2 molecular glue degrader that significantly inhibits MC38 tumor growth in mouse tumor xenograft models. (R)-PVTX-405 can be used in cancer-related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
