2991453-50-8
Chemical Structure
F-CRI1
- CAS No.: 2991453-50-8
- Formula:C23H25FN4O3
- Molecular Weight:424.47
InChIKey: UAIZJLCLNMVKDH-UHFFFAOYSA-N
SMILES: O=C1C2=C(N(C3=C1C=C(C=C3)OC)CC4=CN(N=N4)CCOCCF)C(C)=C(C)C=C2
Biological Activity: F-CRI1 is a STING binding agent. F-CRI1 is radiolabeled with 18F and used as a PET imaging agent to visualize STING expression in tumor microenvironment. F-CRI1 labeled with 19F exhibits fluorescent properties (excitation wavelength: 400 nm) and can be used for flow cytometry and confocal imaging of cells. F-CRI1 can be used for research on colon cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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F-CRI1 | 98.25% | F-CRI1 is a STING binding agent. F-CRI1 is radiolabeled with 18F and used as a PET imaging agent to visualize STING expression in tumor microenvironment. F-CRI1 labeled with 19F exhibits fluorescent properties (excitation wavelength: 400 nm) and can be used for flow cytometry and confocal imaging of cells. F-CRI1 can be used for research on colon cancer. | ||||||||||||||||||||
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References
- [1]. Liu H, et al. Development of F-Labeled Acridone Analogue for Tumor Imaging via Stimulator of Interferon Genes Targeting. Molecular pharmaceutics. 2023 Jul 03;20(7):3529-3538. [Content Brief]
- [2]. Fang J, et al. F-Labeled Amidobenzimidazole Analogue for Visualizing STING Expression in Tumor. Molecular pharmaceutics. 2024 Apr 01;21(4):1942-1951.